© 2016 CAPRI Central Alberta Pain & Rehabilitation Institute

Regenerative Therapy Guidelines

Pre-Treatment Guidelines

 Please read them carefully.


  1. We prefer that you take no NSAID medications (such as Advil, Motrin, Aleve, Aspirin, etc.) either oral (by mouth) or topical (on the skin) for at least one week before and four weeks after your treatment.  Non-NSAID pain relievers (Tylenol, Tramadol) are OK.  Natural anti-inflammatories such as fish oil are OK.  Baby aspirin for heart health is OK.  We also prefer that you not take cholesterol lowering medications known as statins (i.e. Crestor, Lipitor, Pravachol, Zocor) for 1 week before and 4 weeks after your treatment.  However, if your doctor feels it would be dangerous to be off the statins for that long, do not go off of them.

  2. Other than NSAIDs, do not discontinue any of your medications, even anti-coagulant medications.

  3. To minimize risk of infection, please shower the morning of your procedure and put on clean clothes.

  4. Do NOT wear any perfume, cologne, scented lotions, or scented hair products the day of your procedure.

  5. Wear comfortable clothes that are easy to take off and put on, such as slip-on shoes, without laces.

  6. If your blood pressure is too high when we take it here (at or above 180/110), we might postpone your procedure for your safety. If you have high blood pressure, it is a good idea to do a medication check with your doctor before your procedure.

  7. You may receive a mild pre-sedative such as Ativan.

  8. Please eat a light meal before your procedure.

  9. Have realistic expectations and be patient. While we are happy to report that our overall results are excellent, some people don't respond to the treatment. The people that do respond see gradual relief over time; it can take two to four months to get noticeable relief and we expect you will bet maximal benefit around 6 months after injection. So if you are a few weeks out and have not found the results to be great, don’t panic. Please be patient as this is not a quick-fix.

Post-Regenerative Therapy Treatment Guidelines


EXPECT POST-INJECTION SORENESS for 2-10 days following treatment.  Although some patients report no increase in pain, you may experience some increase in pain, or “flare-up”, especially during the first 24 hours after treatment.  Our therapies stimulate healing by causing local inflammation, so soreness is a normal response, please no not panic.


DO NOT USE ANTI-INFLAMMATORY MEDICINES OR ICE on the injection sites for at least four weeks after the treatment.  Medicines such as aspirin, ibuprofen, Naprosyn, or Aleve (either oral or topical) and/or ice stop the inflammatory process that we are intentionally triggering and thus can negate the benefits of treatment.  You may use heat for 15 minutes at a time along with gentle stretching to relieve discomfort. Using acetaminophen (Tylenol or Tramadol), narcotic pain medicines, or muscle relaxants may also relieve pain without interfering with the effect of the treatment.  All natural supplements including natural anti-inflammatory supplements are OK to take.


IT IS CRITICAL TO REST TO ALLOW YOUR TISSUE TO HEAL. For the first week limit activity to 50% normal, and the second week, 75% normal. Avoid repetitive motion, heavy exercise or impact sports for the first week after treatment. Walking, stationary bicycle, and gentle stretches such as yoga are encouraged as tolerated. A common setback is that people will feel better soon after the treatment and then overdo it by deciding to catch up on all the manual work they need to do, such as yard work or housework.


BONE MARROW ASPIRATION SITE - Keep the site covered and dry for 24 hours.


VERY IMPORTANT!  Call the CAPRI Clinic Emergency Contact number (403-550-3447) if you develop signs of infection such as redness, heat and swelling at the site of an injection or aspiration. Infection is an extremely rare complication of these therapies but requires prompt treatment if suspected.  Infection responds very quickly to antibiotic therapy and is not serious if treated immediately. However, if left untreated, infection can very quickly become serious. In the unlikely event that you cannot get a response from the emergency contact number, proceed to the nearest hospital emergency room to rule out “septic joint”.


BE PATIENT WITH THE HEALING PROCESS AND CURB UNREALISTIC EXPECTATIONS. Although some patients notice a reduction in pain within a few days after treatment, much more often the regeneration of tissue takes about 4-6 weeks and continues for months afterwards.  Most often, maximal pain relief is not experienced until 6 months after treatment. Repeating the treatment (Stem cell or PRP injections) after 6 months to 1 year may be necessary to optimize benefits, especially for old chronic injuries or advanced, “bone-on-bone” arthritis.


THINK POSITIVELY! WE ARE ROOTING FOR YOU! We are in this with you and want you to be out of pain and back in the game!